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Allergies in dogs can manifest with as much discomfort as they do in humans, with symptoms ranging from incessant scratching to chronic respiratory issues. Antihistamines have become a cornerstone in managing these allergic reactions, offering relief to our canine companions. In this article, we will navigate through the world of antihistamines to uncover the best options for treating dog allergies. From understanding the causes of allergies to assessing the efficacy and safety of various antihistamine treatments, we’ll provide a comprehensive guide to help you find the most suitable solution for your four-legged friend’s allergy woes.


#1 – iHeartDogs Allergy & Itch Relief for Dogs with Salmon Oil, Quercetin, Colostrum, Antioxidants and Probiotics – 90 Count

The iHeartDogs Allergy & Itch Relief for Dogs is a product that aims to provide relief for dogs suffering from allergies and itchy skin. It contains a blend of natural ingredients that boost the dog’s immune system, alleviating symptoms such as itching, sneezing, scratching, and skin irritation. The product also includes salmon oil, which supports a healthy immune system, heart health, and cognitive function in dogs. Colostrum, known as “mother’s first milk,” provides high levels of antibodies for immune system support, while Reishi mushrooms help control histamines and reduce allergy symptoms.


#2 – Zesty Paws Dog Allergy Relief – Anti Itch Supplement – Omega 3 Probiotics for Dogs – Salmon Oil Digestive Health – Soft Chews for Skin & Seasonal Allergies – with Epicor Pets – Lamb – 90 Count

Zesty Paws Dog Allergy Relief is a supplement designed to support immune, histamine, and digestive health in dogs with skin, seasonal, and environmental allergies. The soft chews contain Epicor Pets, a blend of vitamins, protein, fiber, and antioxidants that are clinically proven to boost the body’s natural immune defenses. Additionally, the supplement includes a powerful Probiotic Complex and Salmon Fish Oil to provide Omega 3 fatty acids that promote healthy skin and immune function.


#3 – Pet Honesty Dog Allergy Relief Immunity – Dog Allergy Chews, Probiotics for Dogs, Seasonal Allergies, Dog Skin and Coat Supplement, Itch Relief for Dogs, Allergy Support Supplement (Salmon)

Pet Honesty Dog Allergy Relief Immunity chews are a natural supplement designed to support dogs with seasonal and occasional allergies. The chews contain a combination of ingredients such as colostrum, salmon oil, turmeric, organic mushrooms, and probiotics to promote a healthy immune system, digestion, and detoxification process. Made in the USA with high-quality ingredients, the chews are free from preservatives, corn, soy, GMOs, and harsh chemicals. Additionally, they include omega-3 fatty acids from wild Alaskan salmon oil to soothe skin-related issues associated with allergies.


#4 – Pro-Sense Itch and Allergy Solutions, 100-count

Pro-Sense Itch and Allergy Solutions is a product that provides temporary relief from allergy symptoms in dogs, such as itching, runny nose, sneezing, and watery eyes. The tablets are formulated with diphenhydramine HCI and are suitable for use only with dogs weighing 15 pounds or more. The bottle contains 100 chewable tablets, allowing pet owners to proactively invest in their pet’s health with sensible healthcare solutions.


#5 – PetArmor Antihistamine Allergy Relief for Dogs, 100 Tablets

PetArmor Antihistamine Allergy Relief for Dogs is an affordable at-home treatment that provides temporary relief for dogs with sensitive itchy skin, insect bites, and stings. These tablets contain the same active ingredient as BENADRYL Allergy ULTRATABS and are easy to use. With 100 tablets in each container, this product offers cost savings for pet owners.


#6 – Vet’s Best Seasonal Allergy Soft Chew Dog Supplements | Soothes Dogs’ Skin Irritation Due To Seasonal Allergies | 30-Day Supply

Vet’s Best Seasonal Allergy Soft Chews for Dogs is a veterinarian-formulated supplement designed to support normal histamine levels in dogs suffering from seasonal allergies. The soft chews are made with natural ingredients like Nettle Leaf, Perilla Seed, and Vitamin E, and can be conveniently given to dogs directly or mixed with their meals. The formula also contains anti-oxidant-rich ocean kelp to aid in absorption, digestion, and immune response. Trusted by pet owners, this product carries the National Animal Supplement Council (NASC) Quality Seal.


#7 – DOGSWELL Remedy + Recovery 0.5% Hydrocortisone Lotion for Dogs, 4 oz. (Packaging May Vary)

The DOGSWELL Remedy + Recovery 0.5% Hydrocortisone Lotion for Dogs is a product designed to alleviate itching, reduce inflammation, and decrease swelling in dogs. It promotes healing and is particularly useful when used in combination with an E-Collar to prevent further irritation. The product comes in a 4 oz. bottle with varying packaging options.


#8 – Pet MD Hydrocortisone Spray for Dogs, Cats, Horses – Itch Relief Spray & Hot Spot Treatment for Dogs, Irritated Dry Itchy Skin, Allergies, and Dermatitis – Reduces Topical Inflammation – 4 oz

The Pet MD Hydrocortisone Spray is a treatment designed to provide itch relief and treat hot spots in dogs, cats, and horses. It effectively reduces inflammation, swelling, itching, and redness, helping to stop the cycle of scratching and biting. The non-stinging formula is fragrance and dye-free, providing relief without causing further irritation to the skin. Additionally, the product is made in the USA, ensuring quality and adherence to strict inspection and quality controls.


What Should I Consider When Buying an Antihistamine for Dog Allergies?

When buying an antihistamine for dog allergies, consider the following:

1. Vet Recommendation: Always consult with your veterinarian before giving your dog any medication. They can recommend the correct antihistamine based on your dog’s specific allergy symptoms and medical history.

2. Active Ingredients: Check the active ingredients to ensure they are safe for dogs. Diphenhydramine, loratadine, and cetirizine are commonly used antihistamines for dogs, but the appropriate one will depend on your dog’s condition.

3. Dosage: The correct dosage is crucial and will vary based on your dog’s size, age, and the severity of the allergies. Overdosing can be dangerous, and underdosing may be ineffective.

4. Formulation: Antihistamines come in various forms, such as tablets, capsules, and liquids. Choose one that you can administer easily to your dog.

5. Side Effects: Be aware of potential side effects, which can include drowsiness, dry mouth, or urinary retention. Observe your dog’s reaction after administering the antihistamine.

6. Frequency of Administration: Some antihistamines need to be given multiple times a day, while others are once-daily. Consider your schedule and your ability to consistently give your dog the medication.

7. Allergy Type: Understand the type of allergy your dog has, as some antihistamines are better for certain reactions, like skin allergies, than others.

8. Interactions with Other Medications: If your dog is on other medications, ensure that the antihistamine will not interact negatively with them.

9. Duration of Treatment: Consider how long the dog will need to be on the antihistamine. Some allergies are seasonal, while others may be chronic.

10. Price: Prices can vary, but the most expensive option is not always the best. Look for a balance between cost and effectiveness.


Frequently Asked Questions About Antihistamines for Dog Allergies

1. Are over-the-counter antihistamines safe for dogs?
Many over-the-counter antihistamines can be safe for dogs, but they must be used under the guidance of a veterinarian. The vet will recommend the correct dosage and inform you of any possible side effects or interactions with other medications your dog may be taking.

2. What are the common side effects of antihistamines in dogs?
Common side effects of antihistamines in dogs include drowsiness, dry mouth, urinary retention, and in some cases, gastrointestinal upset. If you notice any severe reactions or behavioral changes in your dog, contact your vet immediately.

3. How quickly do antihistamines work in dogs?
Antihistamines typically begin to work within an hour of administration, but it might take a few days of consistent use to notice a significant reduction in allergy symptoms. If there’s no improvement after a week, consult your vet.

4. Can all dog breeds take antihistamines?
Most dog breeds can take antihistamines, but some breeds may be more sensitive to certain drugs. Always start with the lowest dose and monitor your dog’s response.

5. How do I determine the right dosage of antihistamines for my dog?
The correct dosage is determined based on the dog’s weight, age, and overall health status. This should be done by a veterinarian to avoid the risk of overdose or ineffective treatment.

6. Can I give my dog antihistamines for a skin allergy?
Yes, antihistamines are often prescribed for skin allergies in dogs. They can help to reduce itching and inflammation, but they may not be effective in all cases and are typically used as part of a broader treatment plan.

7. Will antihistamines cure my dog’s allergies?
Antihistamines do not cure allergies but are used to manage and alleviate the symptoms. Allergy management often requires a multifaceted approach, including environmental changes and, in some cases, prescription medications or allergy shots.

8. Can I give my dog antihistamines daily?
Some antihistamines can be given daily, but it should only be done under the direction of a vet. Long-term use may lead to tolerance, and the medication may become less effective over time.

9. What if my dog doesn’t respond to antihistamines?
If your dog doesn’t respond to antihistamines, there may be other options available, such as corticosteroids or allergy immunotherapy. Your vet can advise you on alternative treatments that might be more effective.

10. Is it safe to use antihistamines for long-term allergy management in dogs?
Long-term use of antihistamines is generally safe under veterinary supervision. However, it’s important to have regular check-ups to monitor your dog’s health and adjust the treatment as necessary.


Conclusion: Best Antihistamine for Dog Allergies

In the end, the well-being of our dogs hinges on our ability to effectively manage their health challenges, including allergies. The best antihistamine for your dog will depend on their specific symptoms, severity of reactions, and overall health profile. It’s imperative to consult with a veterinarian to ensure the chosen antihistamine is the right fit for your pet’s needs. With the right approach and treatment, you can help alleviate your dog’s discomfort and enjoy their company happily and healthily for years to come. Remember, a happy dog makes for a happy home, and finding the correct antihistamine is a step toward that joy.

iHeartDogs is reader-supported. Some of the links below may be paid affiliate links, where we receive a small commission on a product at no additional cost to you. 

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